DeFi (Decentralized Finance) was the “next big trend” of 2020, attracting thousands of new users to the crypto space during that time. Unfortunately, since then, we haven’t seen another true moment of massive industry-wide adoption.
You might argue that prediction markets play a similar role today, but anyone who experienced 2020 knows that the level of excitement back then was unmatched.
My theory is that AI agents will be the next big trend because they can finally make crypto and DeFi easier for everyone to use, thus lowering the barrier to entry for our industry.
In this article, I’ll explain why I believe this so strongly and share with you the top AI agent projects for each specific use case.
Agents Are What Crypto Needs
Besides Bitcoin ($BTC) gradually becoming the “new gold” and a digital store of value, the rest of blockchain technology has struggled to achieve the long-awaited mass adoption.
As mentioned in the introduction, since the birth of DeFi, we have not witnessed another mass influx of users. However, if we have to pinpoint the categories that have performed well in the past few months, they are:
Stablecoins: With centralized solutions like $USDT and $USDC leading the competition.
Prediction Markets: Dominated by @Polymarket and @Kalshi.
Understanding why and how these products have achieved a certain level of adoption will help us see why the crypto space needs agents.
The value proposition of stablecoins is clear: a digital dollar accessible to everyone worldwide. More importantly, getting them is super easy. Today, fiat on-ramp solutions are everywhere, and stablecoins can even be used as savings accounts within mobile apps.
Prediction markets are similar. If you’ve used them, you know they feel just like a Web2 application. No Web3 wallet, no complex on-chain transactions, and no blockchain fees required. Simplicity is key.
The Solution to Making Crypto Inclusive—Simplifying User Experience with AI Agents (UX)
“DeFi was supposed to be finance for everyone: open, permissionless, and fair. But that’s not the reality of DeFi in 2025.”
A term that became popular a few months ago is “AgentFi.” This refers to a set of on-chain financial products that use agents to simplify processes.
For example? A stablecoin agent could move your $USDC across different blockchains to find you the best APY (annual percentage yield) 24/7, nonstop.
Another example? An AI agent helps traders find the best alpha (excess returns) by analyzing on-chain activity, community sentiment (CT sentiment), token allocation, and technical analysis.
If we want to achieve mass adoption, we must simplify crypto, and we can do this by having AI agents handle some of the work.
Top Projects in the AgentFi Narrative
“If you keep operating manually, you will fail.” Humans simply aren’t made for 24/7 markets. Agents are. The sooner you accept this, the more profitable you’ll be.
With this in mind, I want to introduce you to the top projects in the AgentFi space, categorized by the use cases they aim to solve:
Stablecoin Agents for Passive APY
Use case: Imagine an agent controlling your stablecoins and deploying them to different protocols and blockchains every time a new yield opportunity arises.
Top projects:
@ZyfAI_ : Its multi-chain stablecoin agent autonomously moves stablecoins on Arbitrum and Base to optimize APY, even reaching +15% APY.
@SaildotMoney: Another multi-chain stablecoin agent operating on Base and Arbitrum, unique in its ability to split your stablecoin allocations across different protocols.
@gizatechxyz: A pioneer in the field and the first platform able to manage institutional capital. They offer a fixed 15% APY to all users who deposit $USDC .
@yieldseekerxyz: Agents manage your $USDC on Base and provide passive APY. Currently, all depositors receive points, so you’re also “farming a potential airdrop.”
Creating Complex DeFi Strategies via Agents
Use case: What if you could use AI agents to automate complex trading and DeFi strategies?
Top projects:
@symphonyio: A framework that lets you create “Agent Vaults” for agents to execute various on-chain strategies. Currently running on @monad.
@HeyAnonai: An all-in-one terminal that lets users chat with AI agents and automate complex on-chain processes (from trading to DeFi LP strategies) via a ChatGPT-like interface.
@almanak: Just released Strategy Builder, allowing users to create: autonomous trading strategies or autonomous LP strategies.
@glider_fi: A DeFi portfolio automation tool that uses AI to let users create simple but very useful personalized investment indexes, such as the “Big Five” strategy ($BTC, $ETH, $SOL, $XRP , and $DOGE).
AI Agents as Trading Companions
Use case: Trading is one of the biggest use cases in crypto, and AI agents can be used to improve win rates and enhance the entire trading experience.
Top projects:
@Velvet_Capital: A trading terminal with various AI features to help traders throughout the entire process from research to execution.
@Cod3xOrg: Great if you already have a firm trading thesis. You prompt your trading argument, and the agent provides insights and can even act autonomously based on it.
@modenetwork: Released Mode’s AI trading agent, a 100% autonomous entity that trades for you. You just decide which markets and maximum leverage the agent can use, then deposit stablecoins into the agent’s wallet.
@FigmentTrade: A new framework that lets anyone create autonomous trading agents in minutes. Interestingly, once the agent starts trading, it continually shares the reasoning behind each trade, solving the “black box” trust issue for trading agents.
Prediction Agents to Help You Bet Better
Use case: Similar to trading agents, prediction agents help users make better predictions and can even automate the whole process.
Top projects:
@sire_agent: An autonomous prediction agent for betting on different sports markets. Since launch, its win rate has remained at 55-58%.
@polybroapp: Like the ChatGPT of prediction markets: you can ask it to analyze any prediction, and it will give you the probability percentages of different outcomes.
@SemanticLayer: The first framework allowing agents to trade autonomously on Polymarket using the x402 standard. Now, through its “Prophet Arena”, it is evaluating the best AI models used in prediction markets (@grok is currently leading).
@aixbet_ai: A prediction terminal offering high-quality, AI-driven cross-market insights. It tracks sentiment, capital flows, and other metrics.
Tracking the Entire AgentFi Space
What I’ve introduced above is just a small fraction of all the agents out there. Over the past few months, I’ve created a spreadsheet to track all the agents, categorized by their use cases.
If you want to get it, share this article and comment “I want the sheet”.
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Crypto agents are the next major trend
Compiled by: Plain English Blockchain
DeFi (Decentralized Finance) was the “next big trend” of 2020, attracting thousands of new users to the crypto space during that time. Unfortunately, since then, we haven’t seen another true moment of massive industry-wide adoption.
You might argue that prediction markets play a similar role today, but anyone who experienced 2020 knows that the level of excitement back then was unmatched.
My theory is that AI agents will be the next big trend because they can finally make crypto and DeFi easier for everyone to use, thus lowering the barrier to entry for our industry.
In this article, I’ll explain why I believe this so strongly and share with you the top AI agent projects for each specific use case.
Agents Are What Crypto Needs
Besides Bitcoin ($BTC) gradually becoming the “new gold” and a digital store of value, the rest of blockchain technology has struggled to achieve the long-awaited mass adoption.
As mentioned in the introduction, since the birth of DeFi, we have not witnessed another mass influx of users. However, if we have to pinpoint the categories that have performed well in the past few months, they are:
Understanding why and how these products have achieved a certain level of adoption will help us see why the crypto space needs agents.
The value proposition of stablecoins is clear: a digital dollar accessible to everyone worldwide. More importantly, getting them is super easy. Today, fiat on-ramp solutions are everywhere, and stablecoins can even be used as savings accounts within mobile apps.
Prediction markets are similar. If you’ve used them, you know they feel just like a Web2 application. No Web3 wallet, no complex on-chain transactions, and no blockchain fees required. Simplicity is key.
The Solution to Making Crypto Inclusive—Simplifying User Experience with AI Agents (UX)
A term that became popular a few months ago is “AgentFi.” This refers to a set of on-chain financial products that use agents to simplify processes.
For example? A stablecoin agent could move your $USDC across different blockchains to find you the best APY (annual percentage yield) 24/7, nonstop.
Another example? An AI agent helps traders find the best alpha (excess returns) by analyzing on-chain activity, community sentiment (CT sentiment), token allocation, and technical analysis.
If we want to achieve mass adoption, we must simplify crypto, and we can do this by having AI agents handle some of the work.
Top Projects in the AgentFi Narrative
With this in mind, I want to introduce you to the top projects in the AgentFi space, categorized by the use cases they aim to solve:
Stablecoin Agents for Passive APY
Use case: Imagine an agent controlling your stablecoins and deploying them to different protocols and blockchains every time a new yield opportunity arises.
Top projects:
Creating Complex DeFi Strategies via Agents
Use case: What if you could use AI agents to automate complex trading and DeFi strategies?
Top projects:
AI Agents as Trading Companions
Use case: Trading is one of the biggest use cases in crypto, and AI agents can be used to improve win rates and enhance the entire trading experience.
Top projects:
Prediction Agents to Help You Bet Better
Use case: Similar to trading agents, prediction agents help users make better predictions and can even automate the whole process.
Top projects:
Tracking the Entire AgentFi Space
What I’ve introduced above is just a small fraction of all the agents out there. Over the past few months, I’ve created a spreadsheet to track all the agents, categorized by their use cases.
If you want to get it, share this article and comment “I want the sheet”.
Article link: https://www.hellobtc.com/kp/du/12/6153.html
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