Jefferies, a well-known American investment bank, recently released a major report for 2026, directly outlining investment directions across four major sectors. The core theme of this report is two words: Bull Market.



First, the internet sector. $APP is favored because advertising platforms are expected to expand significantly in the first half of the year, targeting a market cap of around $86 billion. $UBER is optimistic due to advancements in robotaxi technology combined with demographic changes. $SPOT's new business lines are expected to boost profit margins, and its pricing power remains strong. $RDDT is growing through data licensing, with increasing user stickiness. $ROKU is positioned as a turnaround target, with improvements in the advertising market providing opportunities. $Z, in the context of a real estate recovery, shows promise in its software services business.

The software sector is more straightforward—focused on AI applications. $NOW is the top choice because it is the most "reliable" in deploying generative AI products. $SHOP's enterprise applications exceeded expectations and are beginning to scale. $TWLO's previous cyclical fluctuations have stabilized, with steady growth in voice AI. $HUBS, as a leading player in AI solutions for small and medium-sized enterprises, is regaining pricing power.

Biotechnology deserves special attention. $DNTH is a preferred target, with Phase III data for neuromuscular diseases expected to be a key milestone in 2026. $TSHA's Rett syndrome gene therapy faces regulatory updates. $TYRA's injectable alternatives in oral health have strong clinical data backing. $TNG's precision oncology pipeline is gradually maturing. $SLDB's gene therapy for Duchenne muscular dystrophy is expected to see new progress. $ORIC's oncology catalysts are anticipated to materialize in the first half of the year.

Quantum computing, a new track, is also highlighted separately. $IONQ, as a leader in pure quantum computing, has ample orders; $QBTS's focus on commercial quantum annealing is rising. 2026 is seen as a breakthrough year for commercial quantum computing.

The mining sector is more straightforward—$FCX has opportunities due to tight copper supply (driven by data center demand), while $GLEN shows valuation differences compared to peers, and its capital return story is quite attractive.

What is the core strategic logic? The institutional approach is: first allocate to internet and software applications, the actual growth drivers, rather than just focusing on infrastructure like chips. Biotechnology investments should target those with clinical data expected in 2026. Quantum computing will be a watershed year in 2026.
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GasFeeTearsvip
· 14h ago
Bull market? Let's see if the chips go up first, that old internet approach is outdated.
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ForkInTheRoadvip
· 18h ago
I agree with internet and software, but do we really want to bet on those Phase III data in biotechnology? Isn't there a risk of splashing?
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VCsSuckMyLiquidityvip
· 18h ago
Hey, wait a minute, it's another AI application story. I've already jumped on NOW and SHOP, now it's just a matter of who can really break out.
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BlockchainBouncervip
· 19h ago
Wait, can biotech really come to fruition in 2026? Feels like the clinical data risk is quite high. This logic is basically about avoiding chip hype and focusing on real implementation. I agree. The combination of internet plus software AI is pretty good, but why are some still bullish below the death cross... Quantum computing breakthrough year? Let me first see if $IONQ's orders can really turn into revenue. I agree with the logic of tight copper supply, but is the cyclical risk in mining really that small?
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rugged_againvip
· 19h ago
Here comes another report trying to shake out retail investors like us. Jefferies' rhetoric is pretty much the same every year.
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ZeroRushCaptainvip
· 19h ago
Bull market? Ha, here comes another report telling me the 2026 story. Wait, the institutions say "safe" now, but I always feel like it's going to get cut in half. Those biotech Phase III data sound just like the last time I went all-in on that one—ended up zeroing out. Quantum computing breakthrough year? Bro, we've heard too many "watershed" moments already. Looking back at this report, I’d rather buy the dip in $IONQ's competitors.
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GasFeeCrybabyvip
· 19h ago
The bull market narrative is starting again. Whether you believe it or not, I definitely do haha. Jefferies' logic this time is quite clear. The combination of Internet + software + biotech is interesting, especially since they are avoiding the chip infrastructure sector. SHOP and NOW are indeed quick to act in AI applications, with enterprise demand right there. But the problem is, valuations are also there. Quantum computing to break through by 2026? Let's see if IONQ can actually deliver. Having many orders doesn't mean commercial deployment is achieved. FCX's copper logic is sound. Data centers are starving, but the only concern is policy changes. It seems that institutions are shifting their focus from hardware to application layers by 2026. I wonder if I should follow the trend and copy the homework.
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ColdWalletGuardianvip
· 19h ago
Bull market, huh? Let's see if SHOP can truly outperform expectations and deliver.
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